CMINDS^® MATRICS^{TM *}- Equivalent Battery

CMINDS^®

CMINDS^® hosts construct-equivalent computerized versions of the neurocognitive assessment instruments constituting the MATRICS^TM Consensus Cognitive Battery (MCCB^TM). Importantly, the CMINDS^® equivalent versions of the MATRICS^TM assessments are primarily based on the same tests, achieving identical face validity and high concurrent validity with the traditional versions.

Concurrent Validity of CMINDS^® Tests vs. MATRICS^TM Tests

To evaluate the concurrent validity of the CMINDS^® computerized test versions vs. a standard Neurocognitive Battery (including tests selected by the MATRICS^TM Consortium), a multicenter study, funded by the National Institute of Mental Health (NIMH), was conducted at several leading clinical centers at the: University of Southern California, Mount Sinai School of Medicine, Long Beach VA Medical Center and University of California, San Diego.

The results were recently presented at the Mount Sinai Conference on Cognition in Schizophrenia (2007)^**, where it was selected as one of the "Top Ten" posters presented, and at the ISCTM Mid-Year Conference (2007)^***. These results have since been published as a full-length article in Schizophrenia Research.

Beyond the MATRICS^TM Battery

Importantly, the CMINDS^® Protocol Designer enables the addition of tests that can extend the range of assessment, enabling clinical trials sponsors and researchers to target additional CNS processes. Alternatively, the Protocol Designer also permits the selection of batteries that may offer a more brief assesssment, if time of administration is a factor under consideration for a given protocol.

*MATRICS^TM is a trademark of MATRICS Assessment, Inc., 914 Westwood Blvd. #512, Los Angeles, CA 90024

^**O'Halloran JP, Gooch K, Harvey P, Kemp AS, Palmer B, Reist C, Rutledge S, Schneider L (2007). Concurrent Validity of a Computerized Neurocognitive Assessment System Encompassing CATIE and MATRICS Batteries. Schizophrenia Bulletin, 33 (2): 571. International Congress on Schizophrenia Research (ICOSR) & the Mount Sinai Conference on Cognition in Schizophrenia; Colorado Springs, CO; March 28 - April 1.

^***Kemp AS, Harvey P, Palmer B, Reist C, Schneider L, Gooch K, O'Halloran JP (2007). Psychometric Comparison of Computerized and Standard Administration of the Neurocognitive Assessment Instruments Selected by the CATIE and MATRICS Consortia among Patients with Schizophrenia. Mid-Year Conference of the International Society for CNS Clinical Trial Methodologies (ISCTM); Brussels, Belgium; September 17-19.