CMINDS® MATRICSTM *- Equivalent
Battery
CMINDS®
CMINDS® hosts construct-equivalent
computerized versions of the neurocognitive assessment instruments constituting
the MATRICSTM Consensus Cognitive Battery
(MCCBTM). Importantly, the CMINDS®
equivalent versions of the MATRICSTM
assessments are primarily based on the same tests, achieving identical face
validity and high concurrent validity with the traditional versions.
Concurrent Validity of CMINDS® Tests
vs. MATRICSTM Tests
To evaluate the concurrent validity of the CMINDS®
computerized test versions vs. a standard Neurocognitive Battery (including
tests selected by the MATRICSTM Consortium), a
multicenter study, funded by the National Institute of Mental Health (NIMH), was
conducted at several leading clinical centers at the: University of Southern
California, Mount Sinai School of Medicine, Long Beach VA Medical Center and
University of California, San Diego.
The results were recently presented at the Mount
Sinai Conference on Cognition in Schizophrenia (2007)**, where it was selected
as one of the "Top Ten" posters presented, and at the ISCTM Mid-Year Conference
(2007)***. These results have
since been published as a full-length
article in Schizophrenia Research.
Beyond the MATRICSTM
Battery
Importantly, the CMINDS® Protocol Designer
enables the addition of tests that can extend the range of assessment, enabling
clinical trials sponsors and researchers to target additional CNS processes.
Alternatively, the Protocol Designer also permits the selection of batteries
that may offer a more brief assesssment, if time of administration is a factor
under consideration for a given protocol.
*MATRICSTM is a trademark of
MATRICS Assessment, Inc., 914 Westwood Blvd. #512, Los Angeles, CA 90024
**O'Halloran JP, Gooch K,
Harvey P, Kemp AS, Palmer B, Reist C, Rutledge S, Schneider L (2007). Concurrent
Validity of a Computerized Neurocognitive Assessment System Encompassing CATIE
and MATRICS Batteries. Schizophrenia Bulletin, 33 (2): 571. International
Congress on Schizophrenia Research (ICOSR) & the Mount Sinai Conference on
Cognition in Schizophrenia; Colorado Springs, CO; March 28 - April 1.
***Kemp AS, Harvey P,
Palmer B, Reist C, Schneider L, Gooch K, O'Halloran JP (2007). Psychometric
Comparison of Computerized and Standard Administration of the Neurocognitive
Assessment Instruments Selected by the CATIE and MATRICS Consortia among
Patients with Schizophrenia. Mid-Year Conference of the International Society
for CNS Clinical Trial Methodologies (ISCTM); Brussels, Belgium; September
17-19.